Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 5/20 | 0.51 |
| ▸ | PPARG | P37231 | 4/20 | 0.51 |
| ▸ | PPARA | Q07869 | 4/20 | 0.51 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9301567 | 0.89 | ACE (0.52) | ACEPPARGPPARAGAAALDH1A1 | |
| SCHEMBL9301035 | 0.89 | ACE (0.64) | ACEPPARGPPARAPPARD | |
| SCHEMBL4459598 | 0.84 | ACE (0.56) | ACEPPARGPPARAIDO1EPHX1 | |
| SCHEMBL9299216 | 0.76 | PPARA (0.62) | ACEPPARGPPARAEPHX1 | |
| SCHEMBL9299211 | 0.76 | PPARA (0.62) | ACEPPARGPPARAEPHX1 | |
| SCHEMBL11516592 | 0.75 | ACE (0.60) | ACEPPARGPPARAPPARD | |
| SCHEMBL9848804 | 0.74 | EPHX1 (0.53) | ACEPPARGPPARAIDO1EPHX1 | |
| SCHEMBL9848809 | 0.74 | EPHX1 (0.53) | ACEPPARGPPARAIDO1EPHX1 | |
| SCHEMBL27360388 | 0.74 | HTT (0.47) | IDO1GAAALDH1A1SMN1; SMN2PKM | |
| SCHEMBL6575981 | 0.73 | MEN1 (0.54) | ACEIDO1GAAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292926-A | Cysteine derivatives | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1994-03-08 | — | — | US | disclosed |
| EP-0326326-A1 | Cysteine derivatives | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1989-08-02 | — | — | EP | disclosed |