SCHEMBL9301037

SCHEMBL9301037

CCc1nc2c(C)cc(C)nc2n1Cc1ccc(-c2ccccc2C(=O)NN)cc1

nearest known ligand 0.81

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 3/20 0.66
AGTR2 P50052 3/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21083808 0.91 AGTR1 (0.62) AGTR1AGTR2
SCHEMBL683347 0.89 AGTR1 (0.67) AGTR1AGTR2
SCHEMBL8872802 0.89 AGTR1 (0.64) AGTR1AGTR2
SCHEMBL8559031 0.88 AGTR1 (0.65) AGTR1AGTR2
SCHEMBL8565668 0.88 AGTR1 (0.62) AGTR1AGTR2
SCHEMBL8558632 0.87 AGTR1 (0.62) AGTR1AGTR2
SCHEMBL9313461 0.84 PPARG (0.70) AGTR1AGTR2
SCHEMBL8873549 0.83 AGTR1 (0.62) AGTR1AGTR2
SCHEMBL5434268 0.83 AGTR1 (0.68) AGTR1AGTR2
SCHEMBL8561056 0.82 AGTR1 (0.63) AGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5338737-A Biphenyl oxadiazoles and thiadiazoles as angiotensin II antagonists WARNER-LAMBERT COMPANY (US) 1994-08-16 US disclosed
US-5210204-A Hypotensive agents and cardiovascular disorders WARNER-LAMBERT COMPANY (US) 1993-05-11 US disclosed