Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5075884 | 0.87 | FDPS (0.45) | FDPSTSHRPPARD | |
| SCHEMBL6670360 | 0.87 | FDPS (0.45) | FDPSTSHRPPARD | |
| SCHEMBL9301070 | 0.86 | FDPS (0.37) | FDPSTSHR | |
| SCHEMBL9301453 | 0.85 | FDPS (0.36) | FDPSTSHR | |
| SCHEMBL9303056 | 0.82 | FDPS (0.34) | FDPS | |
| SCHEMBL9301175 | 0.80 | FDPS (0.33) | FDPS | |
| SCHEMBL22991373 | 0.80 | POLB (0.34) | TSHR | |
| SCHEMBL9302389 | 0.79 | FDPS (0.58) | FDPS | |
| SCHEMBL9302643 | 0.78 | FDPS (0.38) | FDPSTSHRPPARD | |
| SCHEMBL9301817 | 0.78 | FDPS (0.38) | FDPSTSHRPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5350743-A | Treatment of osteoporosis | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1994-09-27 | — | — | US | disclosed |
| EP-0498424-A1 | Bisphosphonic acid derivatives and bone resorption inhibitors containing them | Kaken Pharmaceutical Co., Ltd. (JP) | 1992-08-12 | — | — | EP | disclosed |