Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302623 | 0.89 | FDPS (0.37) | FDPSTSHR | |
| SCHEMBL9300897 | 0.88 | FDPS (0.36) | FDPSTSHR | |
| SCHEMBL5075884 | 0.87 | FDPS (0.45) | FDPSTSHRPPARD | |
| SCHEMBL6670360 | 0.87 | FDPS (0.45) | FDPSTSHRPPARD | |
| SCHEMBL9302275 | 0.86 | FDPS (0.37) | FDPSTSHR | |
| SCHEMBL9302299 | 0.84 | OPRM1 (0.36) | FDPS | |
| SCHEMBL9301941 | 0.82 | KDM4E (0.38) | FDPSTSHR | |
| SCHEMBL9300995 | 0.82 | OPRM1 (0.38) | FDPS | |
| SCHEMBL9300869 | 0.82 | FDPS (0.38) | FDPS | |
| SCHEMBL9301452 | 0.81 | FDPS (0.33) | FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5350743-A | Treatment of osteoporosis | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1994-09-27 | — | — | US | disclosed |
| EP-0498424-A1 | Bisphosphonic acid derivatives and bone resorption inhibitors containing them | Kaken Pharmaceutical Co., Ltd. (JP) | 1992-08-12 | — | — | EP | disclosed |