2-Picolinic Acid

2-Picolinic Acid

SCHEMBL9301355

O=C(O)c1ccccn1.O=CO

nearest known ligand 0.83

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.83
L3MBTL1 Q9Y468 2/20 0.83
NAPRT Q6XQN6 1/20 0.83
P4HTM Q9NXG6 1/20 0.83
CES2 O00748 1/20 0.59
CES1 P23141 1/20 0.59
KMT2A Q03164 2/20 0.57
ALDH1A1 P00352 2/20 0.55
KDM4E B2RXH2 4/20 0.53
MAPT P10636 2/20 0.53
NPC1 O15118 1/20 0.53
PKM P14618 1/20 0.53
RAB9A P51151 1/20 0.53
GSK3B P49841 1/20 0.50
TDP1 Q9NUW8 2/20 0.46
ALOX15 P16050 1/20 0.46
TSHR P16473 1/20 0.46
ACMSD Q8TDX5 1/20 0.46
GPR52 Q9Y2T5 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Picolinic Acid SCHEMBL28492646 0.98 LMNA (0.80) LMNAL3MBTL1NAPRTP4HTMCES2
2-Picolinic Acid SCHEMBL29368665 0.91
2-Picolinic Acid SCHEMBL28737810 0.91 LMNA (1.00) LMNAL3MBTL1NAPRTP4HTMCES2
2-Picolinic Acid SCHEMBL674837 0.91 LMNA (1.00) LMNAL3MBTL1NAPRTP4HTMCES2
2-Picolinic Acid SCHEMBL7457912 0.91 LMNA (1.00) LMNAL3MBTL1NAPRTP4HTMCES2
2-Picolinic Acid SCHEMBL36055 0.91
2-Picolinic Acid SCHEMBL27796738 0.90 LMNA (0.80) LMNAL3MBTL1NAPRTP4HTMCES2
2-Picolinic Acid SCHEMBL5667302 0.89 LMNA (0.95) LMNAL3MBTL1NAPRTP4HTMCES2
2-Picolinic Acid SCHEMBL5058102 0.89 LMNA (0.95) LMNAL3MBTL1NAPRTP4HTMCES2
2-Picolinic Acid SCHEMBL20721125 0.89 LMNA (0.95) LMNAL3MBTL1NAPRTP4HTMCES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105037809-A Co-modified LDS (laser direct structuring) additive and PA66 composition containing same LIU SHUAI 2015-11-11 CN disclosed
CN-105001453-A Modified LDS addictive and PC composition containing same LIU SHUAI 2015-10-28 CN disclosed
CN-104961922-A Co-modified LDS (Laser Direct Structuring) additive and LCP (Liquid Crystal Polymer) composition containing same LIU SHUAI 2015-10-07 CN disclosed
CN-104961921-A Modified LDS (Laser Direct Structuring) additive and ABS (Acrylonitrile Butadiene Styrene) composition containing same LIU SHUAI 2015-10-07 CN disclosed
CN-104961923-A Co-modified LDS (Laser Direct Structuring) additive and ABS (Acrylonitrile Butadiene Styrene) composition containing same LIU SHUAI 2015-10-07 CN disclosed
CN-104961916-A Modified LDS (Laser Direct Structuring) additive and LCP (Liquid Crystal Polymer) composition containing same LIU SHUAI 2015-10-07 CN disclosed
CN-104961915-A Co-modified LDS (Laser Direct Structuring) additive and PC composition containing additive LIU SHUAI 2015-10-07 CN disclosed
CN-104945667-A Modified LDS annexing agent and PPS composition containing modified LDS annexing agent LIU SHUAI 2015-09-30 CN disclosed
CN-104945669-A Co-modified LDS annexing agent and PPS composition containing co-modified LDS annexing agent LIU SHUAI 2015-09-30 CN disclosed
CN-104945668-A Modified LDS addition agent and PA66 composition containing same LIU SHUAI 2015-09-30 CN disclosed
US-5306399-A Flowing solution through cation exchange resin, then through anion exchange resin in central compartment of electrochemical cell, applying electric current to cell to cause ion migration and replacement ELECTRIC POWER RESEARCH INSTITUTE (US) 1994-04-26 US disclosed