Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | BAD | Q92934 | 1/20 | 0.39 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9301473 | 1.00 | ALDH1A1 (0.41) | ALDH1A1LMNAGAACYP1A2CYP2C19 | |
| SCHEMBL9621919 | 0.80 | CYP1A2 (0.37) | ALDH1A1CYP1A2CYP2C19MAPTNPC1 | |
| SCHEMBL9621921 | 0.80 | CYP1A2 (0.37) | ALDH1A1CYP1A2CYP2C19MAPTNPC1 | |
| SCHEMBL9301230 | 0.80 | CYP1A2 (0.36) | ALDH1A1LMNACYP1A2CYP2C19MAPT | |
| SCHEMBL9301239 | 0.80 | CYP1A2 (0.36) | ALDH1A1LMNACYP1A2CYP2C19MAPT | |
| SCHEMBL9420136 | 0.79 | CYP1A2 (0.41) | ALDH1A1GAACYP1A2CYP2C19MAPT | |
| SCHEMBL9420140 | 0.79 | CYP1A2 (0.41) | ALDH1A1GAACYP1A2CYP2C19MAPT | |
| SCHEMBL9300976 | 0.79 | CES2 (0.40) | ALDH1A1LMNACYP1A2CYP2C19MAPT | |
| SCHEMBL9621635 | 0.77 | SMN1; SMN2 (0.36) | ALDH1A1LMNACYP1A2CYP2C19MAPT | |
| SCHEMBL9621636 | 0.77 | SMN1; SMN2 (0.36) | ALDH1A1LMNACYP1A2CYP2C19MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5369109-A | Optically active esters of 7-substituted 3,5-difunctionalized 6-heptenoic acids | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1994-11-29 | — | — | US | disclosed |
| EP-0475627-B1 | Optically active esters of 7-substituted 3,5-difunctionalized 6-heptenoic acids | SAGAMI CHEM RES (JP) | 1994-10-19 | — | — | EP | disclosed |
| US-5276154-A | Optically active esters of 7-substituted 3,5-difunctionalized 6-heptenoic acids | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0475627-A1 | Optically active esters of 7-substituted 3,5-difunctionalized 6-heptenoic acids | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1992-03-18 | — | — | EP | disclosed |