Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9300482 | 0.89 | FDPS (0.40) | FDPS | |
| SCHEMBL9301175 | 0.87 | FDPS (0.33) | FDPS | |
| SCHEMBL9301573 | 0.79 | FDPS (0.52) | FDPS | |
| SCHEMBL9302063 | 0.79 | LPAR3 (0.40) | — | |
| SCHEMBL9303056 | 0.75 | FDPS (0.34) | FDPS | |
| SCHEMBL9301453 | 0.71 | FDPS (0.36) | FDPS | |
| SCHEMBL9302389 | 0.69 | FDPS (0.58) | FDPS | |
| SCHEMBL13599357 | 0.69 | HRH3 (0.34) | — | |
| SCHEMBL9301316 | 0.67 | FDPS (0.56) | FDPS | |
| SCHEMBL203348 | 0.67 | FDPS (0.75) | FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5350743-A | Treatment of osteoporosis | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1994-09-27 | — | — | US | claimed |
| EP-0498424-A1 | Bisphosphonic acid derivatives and bone resorption inhibitors containing them | Kaken Pharmaceutical Co., Ltd. (JP) | 1992-08-12 | — | — | EP | claimed |
| US-5350743-A | Treatment of osteoporosis | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1994-09-27 | — | — | US | disclosed |
| EP-0498424-A1 | Bisphosphonic acid derivatives and bone resorption inhibitors containing them | Kaken Pharmaceutical Co., Ltd. (JP) | 1992-08-12 | — | — | EP | disclosed |