Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 20/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303290 | 0.90 | CYP3A4 (0.35) | PTGER4 | |
| SCHEMBL9304108 | 0.89 | RARA (0.39) | PTGER4 | |
| SCHEMBL9302600 | 0.89 | CYP26A1 (0.33) | PTGER4 | |
| SCHEMBL9302094 | 0.85 | — | — | |
| SCHEMBL9301914 | 0.84 | PTGER4 (0.35) | PTGER4 | |
| SCHEMBL9301905 | 0.83 | PTGER4 (0.38) | PTGER4 | |
| SCHEMBL9303922 | 0.81 | CYP3A4 (0.37) | — | |
| SCHEMBL9304041 | 0.78 | RARA (0.41) | PTGER4 | |
| SCHEMBL9817676 | 0.78 | FFAR1 (0.47) | — | |
| SCHEMBL6664615 | 0.77 | CYP3A4 (0.35) | PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354752-A | A dimethylthiochroman or dimethylchroman-6-yl-ethynyl-pyridazin- or pyrimidin- or pyrazin-for treating skin disorders psoriasis | ALLERGAN, INC. (US) | 1994-10-11 | — | — | US | claimed |