Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | IKBKE | Q14164 | 2/20 | 0.33 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9157144 | 0.78 | CHRNB4 (0.46) | CHRNB4CHRNA3 | |
| SCHEMBL9159853 | 0.75 | — | — | |
| SCHEMBL4305262 | 0.75 | HRH3 (0.38) | — | |
| SCHEMBL9157591 | 0.73 | SLC5A2 (0.32) | — | |
| SCHEMBL12524494 | 0.72 | RECQL (0.50) | RECQL | |
| SCHEMBL27370536 | 0.72 | PIK3CD (0.44) | RECQLIKBKETBK1 | |
| SCHEMBL9156445 | 0.71 | CYP11B1 (0.40) | — | |
| SCHEMBL9303942 | 0.69 | ACHE (0.45) | RECQL | |
| SCHEMBL23718482 | 0.67 | SMYD3 (0.35) | — | |
| SCHEMBL9156618 | 0.67 | PIM1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5308852-A | Cardiovascular disorders | MERCK FROSST CANADA, INC. (CA) | 1994-05-03 | — | — | US | disclosed |