Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | PTPRC | P08575 | 2/20 | 0.53 |
| ▸ | CDC25B | P30305 | 3/20 | 0.47 |
| ▸ | TDP2 | O95551 | 3/20 | 0.46 |
| ▸ | NSD2 | O96028 | 3/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | S100A4 | P26447 | 6/20 | 0.44 |
| ▸ | PADI1 | Q9ULC6 | 3/20 | 0.43 |
| ▸ | PADI3 | Q9ULW8 | 3/20 | 0.43 |
| ▸ | PADI4 | Q9UM07 | 3/20 | 0.43 |
| ▸ | PADI2 | Q9Y2J8 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302208 | 0.88 | TDP1 (0.55) | TDP1MEN1THRBBLMKMT2A | |
| SCHEMBL9302015 | 0.84 | GAA (0.55) | TDP1MEN1THRBBLMKMT2A | |
| SCHEMBL9849269 | 0.78 | ELANE (0.53) | TDP1MEN1THRBBLMKMT2A | |
| SCHEMBL730769 | 0.77 | MEN1 (0.90) | TDP1MEN1THRBBLMKMT2A | |
| SCHEMBL29503833 | 0.77 | MEN1 (0.90) | TDP1MEN1THRBBLMKMT2A | |
| SCHEMBL29117498 | 0.76 | ELANE (0.55) | TDP1MEN1THRBBLMKMT2A | |
| SCHEMBL9301218 | 0.76 | TDP1 (0.60) | TDP1MEN1THRBBLMKMT2A | |
| SCHEMBL1899280 | 0.75 | PTPRC (0.88) | TDP1MEN1THRBBLMKMT2A | |
| SCHEMBL29566445 | 0.75 | PTPRC (0.88) | TDP1MEN1THRBBLMKMT2A | |
| Bromide SCHEMBL28112336 | 0.75 | MEN1 (0.86) | TDP1MEN1THRBBLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994009002-A1 | 2-(AZA-9-FLUORENONYL)CARBAPENEM ANTIBACTERIAL AGENTS | MERCK & CO., INC. (US) | 1994-04-28 | — | — | WO | disclosed |
| US-5294610-A | Staphylococcus; side effect reduction | MERCK & CO. INC. (US) | 1994-03-15 | — | — | US | disclosed |