Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 7/20 | 0.48 |
| ▸ | RAB9A | P51151 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | PLA2G1B | P04054 | 3/20 | 0.48 |
| ▸ | ATG4B | Q9Y4P1 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | CASP3 | P42574 | 2/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29117498 | 0.98 | ELANE (0.55) | ELANENPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL9684483 | 0.79 | ALDH1A1 (0.35) | ELANENPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL9685943 | 0.79 | PKM (0.41) | ALDH1A1SMN1; SMN2MAPK1MAPTTSHR | |
| SCHEMBL9685898 | 0.79 | BCL2 (0.39) | ELANENPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL9302208 | 0.78 | TDP1 (0.55) | ATG4BMAPTTDP1MEN1KMT2A | |
| SCHEMBL8896514 | 0.78 | MAPT (0.44) | ELANENPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL9301675 | 0.78 | TDP1 (0.55) | ALDH1A1ATG4BMAPTTDP1MEN1 | |
| SCHEMBL9302015 | 0.78 | GAA (0.55) | ALDH1A1ATG4BMAPTTDP1MEN1 | |
| SCHEMBL9685942 | 0.78 | ELANE (0.33) | ELANENPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL9684470 | 0.77 | HTR7 (0.46) | NPC1RAB9AALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0444889-A1 | Novel synthesis of carbapenem intermediates | MERCK & CO. INC. (US) | 1991-09-04 | — | — | EP | disclosed |