Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | PTPRC | P08575 | 2/20 | 0.54 |
| ▸ | CTSL | P07711 | 1/20 | 0.54 |
| ▸ | CTSS | P25774 | 1/20 | 0.54 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.54 |
| ▸ | TDP2 | O95551 | 3/20 | 0.50 |
| ▸ | NSD2 | O96028 | 3/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CDC25B | P30305 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | S100A4 | P26447 | 5/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302208 | 0.94 | TDP1 (0.55) | GAAPTPRCCTSLCTSSPTPN13 | |
| SCHEMBL9301675 | 0.84 | TDP1 (0.55) | GAAPTPRCCTSLCTSSPTPN13 | |
| SCHEMBL29117498 | 0.79 | ELANE (0.55) | PTPRCCTSLCTSSPTPN13TDP2 | |
| SCHEMBL9849269 | 0.78 | ELANE (0.53) | PTPRCCTSLCTSSPTPN13TDP2 | |
| SCHEMBL9300812 | 0.76 | GAA (0.60) | GAAPTPRCCTSLCTSSPTPN13 | |
| SCHEMBL20089622 | 0.76 | GAA (0.60) | GAAPTPRCCTSLCTSSPTPN13 | |
| SCHEMBL30799541 | 0.75 | PTPRC (0.91) | GAAPTPRCCTSLCTSSPTPN13 | |
| SCHEMBL69772 | 0.75 | PTPRC (0.91) | GAAPTPRCCTSLCTSSPTPN13 | |
| SCHEMBL5915061 | 0.75 | GAA (0.86) | GAAPTPRCCTSLCTSSPTPN13 | |
| SCHEMBL29551149 | 0.73 | GAA (1.00) | GAAPTPRCCTSLCTSSPTPN13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994009002-A1 | 2-(AZA-9-FLUORENONYL)CARBAPENEM ANTIBACTERIAL AGENTS | MERCK & CO., INC. (US) | 1994-04-28 | — | — | WO | disclosed |
| US-5294610-A | Staphylococcus; side effect reduction | MERCK & CO. INC. (US) | 1994-03-15 | — | — | US | disclosed |