Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12378236 | 0.81 | L3MBTL1 (0.55) | ACLYL3MBTL1ALDH1A1SLC40A1TDP1 | |
| SCHEMBL5700122 | 0.81 | L3MBTL1 (0.55) | ACLYL3MBTL1ALDH1A1SLC40A1TDP1 | |
| SCHEMBL30547366 | 0.81 | L3MBTL1 (0.55) | ACLYL3MBTL1ALDH1A1SLC40A1TDP1 | |
| SCHEMBL17675152 | 0.80 | SYK (0.38) | L3MBTL1ALDH1A1SLC40A1TLR7TDP1 | |
| SCHEMBL22827577 | 0.80 | CA1 (0.57) | ACLYL3MBTL1ALDH1A1SLC40A1TDP1 | |
| SCHEMBL12378235 | 0.80 | L3MBTL1 (0.54) | ACLYL3MBTL1ALDH1A1SLC40A1TDP1 | |
| SCHEMBL29910209 | 0.80 | CA1 (0.57) | ACLYL3MBTL1ALDH1A1SLC40A1TDP1 | |
| SCHEMBL20787063 | 0.79 | L3MBTL1 (0.53) | ACLYL3MBTL1ALDH1A1SLC40A1TDP1 | |
| SCHEMBL30547377 | 0.79 | L3MBTL1 (0.53) | ACLYL3MBTL1ALDH1A1SLC40A1TDP1 | |
| SCHEMBL22827859 | 0.78 | L3MBTL1 (0.51) | ACLYL3MBTL1ALDH1A1SLC40A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994009002-A1 | 2-(AZA-9-FLUORENONYL)CARBAPENEM ANTIBACTERIAL AGENTS | MERCK & CO., INC. (US) | 1994-04-28 | — | — | WO | disclosed |
| US-5294610-A | Staphylococcus; side effect reduction | MERCK & CO. INC. (US) | 1994-03-15 | — | — | US | disclosed |