Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 3/20 | 0.52 |
| ▸ | NSD2 | O96028 | 2/20 | 0.50 |
| ▸ | G6PD | P11413 | 2/20 | 0.50 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.50 |
| ▸ | BCL2 | P10415 | 2/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | PTPRC | P08575 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
| ▸ | EDNRB | P24530 | 1/20 | 0.38 |
| ▸ | EDNRA | P25101 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28498561 | 0.78 | MAOB (0.55) | S100A4NSD2G6PDDNMT1PTPRC | |
| SCHEMBL9301644 | 0.77 | S100A4 (0.48) | S100A4BCL2MCL1PTPRCPOLB | |
| SCHEMBL9301771 | 0.76 | BCL2 (0.49) | S100A4BCL2MCL1PTPRCEDNRB | |
| SCHEMBL9302326 | 0.76 | S100A4 (0.47) | S100A4BCL2MCL1PTPRCPOLB | |
| SCHEMBL3722975 | 0.75 | S100A4 (0.59) | S100A4NSD2G6PDDNMT1PTPRC | |
| SCHEMBL762135 | 0.74 | S100A4 (0.80) | S100A4BCL2MCL1PTPRCEDNRB | |
| SCHEMBL39700 | 0.74 | S100A4 (0.90) | S100A4BCL2MCL1PTPRCEDNRB | |
| SCHEMBL29390614 | 0.74 | S100A4 (0.90) | S100A4BCL2MCL1PTPRCEDNRB | |
| SCHEMBL29664078 | 0.74 | S100A4 (0.80) | S100A4BCL2MCL1PTPRCEDNRB | |
| SCHEMBL3717374 | 0.74 | S100A4 (0.80) | S100A4BCL2MCL1PTPRCEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994009002-A1 | 2-(AZA-9-FLUORENONYL)CARBAPENEM ANTIBACTERIAL AGENTS | MERCK & CO., INC. (US) | 1994-04-28 | — | — | WO | disclosed |
| US-5294610-A | Staphylococcus; side effect reduction | MERCK & CO. INC. (US) | 1994-03-15 | — | — | US | disclosed |