Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 2/20 | 0.47 |
| ▸ | BCL2 | P10415 | 2/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | USP7 | Q93009 | 6/20 | 0.43 |
| ▸ | USP47 | Q96K76 | 4/20 | 0.43 |
| ▸ | PTPRC | P08575 | 1/20 | 0.42 |
| ▸ | USP8 | P40818 | 7/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9301241 | 0.78 | USP8 (0.41) | USP7USP47USP8MAOB | |
| SCHEMBL24873135 | 0.76 | USP7 (0.72) | S100A4BCL2MCL1USP7USP47 | |
| SCHEMBL9301758 | 0.76 | S100A4 (0.52) | S100A4BCL2MCL1PTPRCPOLB | |
| SCHEMBL9301644 | 0.73 | S100A4 (0.48) | S100A4BCL2MCL1PTPRCPOLB | |
| SCHEMBL9301771 | 0.72 | BCL2 (0.49) | S100A4BCL2MCL1USP7USP47 | |
| SCHEMBL11624231 | 0.71 | S100A4 (0.61) | S100A4BCL2MCL1USP7PTPRC | |
| SCHEMBL762135 | 0.71 | S100A4 (0.80) | S100A4BCL2MCL1PTPRCCA1 | |
| SCHEMBL29390614 | 0.71 | S100A4 (0.90) | S100A4BCL2MCL1PTPRCCA1 | |
| SCHEMBL39700 | 0.71 | S100A4 (0.90) | S100A4BCL2MCL1PTPRCCA1 | |
| SCHEMBL29664078 | 0.71 | S100A4 (0.80) | S100A4BCL2MCL1PTPRCCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994009002-A1 | 2-(AZA-9-FLUORENONYL)CARBAPENEM ANTIBACTERIAL AGENTS | MERCK & CO., INC. (US) | 1994-04-28 | — | — | WO | disclosed |
| US-5294610-A | Staphylococcus; side effect reduction | MERCK & CO. INC. (US) | 1994-03-15 | — | — | US | disclosed |