Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.53 |
| ▸ | THRA | P10827 | 3/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9301954 | 1.00 | THRB (0.53) | THRBTHRAF2HTTKMT2A | |
| SCHEMBL2827602 | 1.00 | THRB (0.53) | THRBTHRAF2HTTKMT2A | |
| SCHEMBL11410595 | 0.99 | THRB (0.55) | THRBTHRAF2HTTKMT2A | |
| SCHEMBL11412254 | 0.99 | THRB (0.55) | THRBTHRAF2HTTKMT2A | |
| SCHEMBL11422546 | 0.96 | F2 (0.52) | THRBTHRAF2HTTKMT2A | |
| SCHEMBL7941973 | 0.96 | THRB (0.56) | THRBTHRAF2HTTKMT2A | |
| SCHEMBL2829784 | 0.96 | THRB (0.56) | THRBTHRAF2HTTKMT2A | |
| SCHEMBL11412043 | 0.95 | F2 (0.51) | THRBTHRAF2HTTKMT2A | |
| SCHEMBL9302511 | 0.95 | F2 (0.51) | THRBTHRAF2HTTKMT2A | |
| SCHEMBL9189717 | 0.95 | F2 (0.51) | THRBTHRAF2HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5318721-A | Nematic liquid-crystalline phases | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-06-07 | — | — | US | disclosed |
| US-5286410-A | Positive dielectric anisotropy | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-02-15 | — | — | US | disclosed |
| US-5211878-A | Difluorobenzonitrile derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-05-18 | — | — | US | disclosed |
| US-5178790-A | With excellent steepness of characteristics | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1993-01-12 | — | — | US | disclosed |