Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 5/20 | 0.56 |
| ▸ | THRA | P10827 | 3/20 | 0.56 |
| ▸ | F2 | P00734 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7941973 | 1.00 | THRB (0.56) | THRBTHRAF2HTTKMT2A | |
| SCHEMBL7948354 | 0.99 | THRB (0.59) | THRBTHRAF2HTTKMT2A | |
| SCHEMBL7948352 | 0.99 | THRB (0.59) | THRBTHRAF2HTTKMT2A | |
| SCHEMBL9301954 | 0.96 | THRB (0.53) | THRBTHRAF2HTTKMT2A | |
| SCHEMBL9301959 | 0.96 | THRB (0.53) | THRBTHRAF2HTTKMT2A | |
| SCHEMBL2827602 | 0.96 | THRB (0.53) | THRBTHRAF2HTTKMT2A | |
| SCHEMBL11410595 | 0.95 | THRB (0.55) | THRBTHRAF2HTTKMT2A | |
| SCHEMBL11412254 | 0.95 | THRB (0.55) | THRBTHRAF2HTTKMT2A | |
| SCHEMBL9398375 | 0.95 | F2 (0.54) | THRBTHRAF2HTTKMT2A | |
| SCHEMBL9398371 | 0.95 | F2 (0.54) | THRBTHRAF2HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599562-B9 | NEMATIC LIQUID CRYSTAL MIXTURES FOR BISTABLE DISPLAY DEVICES | NEMOPTIC (FR) | 2008-09-24 | — | — | EP | claimed |
| EP-1599562-B1 | NEMATIC LIQUID CRYSTAL MIXTURES FOR BISTABLE DISPLAY DEVICES | NEMOPTIC (FR) | 2007-05-16 | — | — | EP | claimed |
| US-7115307-B2 | Nematic liquid crystal mixtures for bistable display device | NEMOPTIC (FR) | 2006-10-03 | — | — | US | claimed |
| US-RE37270-E1 | EXCELLENT ELECTRO-OPTIC STEEPNESS AND VIEWING ANGLE COMBINED WITH BIREFRINGENCE FOR USE IN STANDARD DISPLAY CELLS; MIXTURE OF 4-CYANO-3-FLUOROPHENYL BENZOATES, BENZONITRILES, ALKYLPHENYL ESTERS OF CYCLOHEXANE OR PHENYLCARBOXYLIC ACIDS | MERCK PATENT GESELLSCHAFT (DE) | 2001-07-10 | — | — | US | claimed |
| EP-0285617-B1 | LIQUID CRYSTAL PHASE | MERCK PATENT GmbH (DE) | 1991-12-27 | — | — | EP | claimed |
| US-4886621-A | ACCEPTABLE COMBINATION OF THRESHOLD STEEPNESS, VIEWING ANGLE AND TEMPERATURE DEPENDENCE AT LOW THRESHOLD VOLTAGE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-12-12 | — | — | US | claimed |
| US-20100264368-A1 | LIQUID CRYSTAL MOLECULES COMPRISING HYDROAZULENE STRUCTURES | TETRAGON-CHEMIE AG (LI) | 2010-10-21 | — | — | US | disclosed |
| EP-1896552-B1 | LIQUID CRYSTAL MOLECULES COMPRISING HYDROAZULENE STRUCTURES | TETRAGON CHEMIE AG (LI) | 2010-05-19 | — | — | EP | disclosed |
| US-RE37270-E1 | EXCELLENT ELECTRO-OPTIC STEEPNESS AND VIEWING ANGLE COMBINED WITH BIREFRINGENCE FOR USE IN STANDARD DISPLAY CELLS; MIXTURE OF 4-CYANO-3-FLUOROPHENYL BENZOATES, BENZONITRILES, ALKYLPHENYL ESTERS OF CYCLOHEXANE OR PHENYLCARBOXYLIC ACIDS | MERCK PATENT GESELLSCHAFT (DE) | 2001-07-10 | — | — | US | disclosed |
| US-5958290-A | ELECTROOPTICAL APPARATUS WITH DIELECTRIC LIQUID CRYSTALS FOR RADIATION TRANSPARENT MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-09-28 | — | — | US | disclosed |
| US-5344587-A | Nitriles | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-09-06 | — | — | US | disclosed |
| WO-1993005436-A1 | ELECTROOPTICAL LIQUID CRYSTAL SYSTEM | MERK PATENT GESELLSCHAFT MIT BESCHRÄNKTER HAFTUNG (DE) | 1993-03-18 | — | — | WO | disclosed |
| EP-0317587-B1 | LIQUID CRYSTAL PHASE | MERCK PATENT GmbH (DE) | 1992-01-02 | — | — | EP | disclosed |
| US-4886621-A | ACCEPTABLE COMBINATION OF THRESHOLD STEEPNESS, VIEWING ANGLE AND TEMPERATURE DEPENDENCE AT LOW THRESHOLD VOLTAGE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-12-12 | — | — | US | disclosed |
| EP-0317587-A1 | LIQUID CRYSTAL PHASE. | MERCK PATENT GMBH (DE) | 1989-05-31 | — | — | EP | disclosed |
| WO-1988009360-A1 | LIQUID CRYSTAL PHASE | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1988-12-01 | — | — | WO | disclosed |
| EP-0285617-A1 | LIQUID CRYSTAL PHASE. | MERCK PATENT GMBH (DE) | 1988-10-12 | — | — | EP | disclosed |
| US-4751017-A | LIQUID CRYSTALS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1988-06-14 | — | — | US | disclosed |
| WO-1988002018-A1 | LIQUID CRYSTAL PHASE | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1988-03-24 | — | — | WO | disclosed |
| US-4715984-A | DIELECTRICS FOR ELECTROOPTICAL DISPLAY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1987-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100264368-A1 | LIQUID CRYSTAL MOLECULES COMPRISING HYDROAZULENE STRUCTURES | FLI1, F12, GTF2I | THRB 1252/4885THRA 938/4885F2 83/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.