Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.53 |
| ▸ | MDM4 | O15151 | 1/20 | 0.53 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8603038 | 1.00 | ATM (0.58) | ATMKLK5ALDH1A1THRBCYP2C9 | |
| SCHEMBL11406714 | 1.00 | ATM (0.58) | ATMKLK5ALDH1A1THRBCYP2C9 | |
| SCHEMBL6549557 | 1.00 | ATM (0.58) | ATMKLK5ALDH1A1THRBCYP2C9 | |
| Hydrochloric Acid SCHEMBL9492789 | 0.99 | ATM (0.56) | ATMKLK5ALDH1A1THRBCYP2C9 | |
| SCHEMBL8603938 | 0.93 | ATM (0.59) | ATMKLK5ALDH1A1THRBCYP2C9 | |
| SCHEMBL8603937 | 0.93 | ATM (0.59) | ATMKLK5ALDH1A1THRBCYP2C9 | |
| Hydrochloric Acid SCHEMBL10412319 | 0.92 | ATM (0.58) | ATMKLK5ALDH1A1THRBCYP2C9 | |
| SCHEMBL8086148 | 0.92 | ALDH1A1 (0.55) | ATMKLK5ALDH1A1THRBCYP2C9 | |
| SCHEMBL237136 | 0.89 | ACE (0.57) | ATMKLK5 | |
| SCHEMBL22013341 | 0.89 | ATM (0.60) | ATMKLK5ALDH1A1THRBCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0334236-B1 | Preparation of n-protected alpha-l-aspartyl-l-phenylalanine methyl ester | MITSUI TOATSU CHEMICALS (JP) | 1994-08-31 | — | — | EP | disclosed |
| US-5302743-A | Reacting N-protected L-aspartic anhydride with L-phenylalanine methyl ester salt in non-aqueous solvent | MITSUI TOATSU CHEMICALS, INC. (JP) | 1994-04-12 | — | — | US | disclosed |
| US-4549987-A | DEFORMYLATION AND SEPARATION OF N-FORMYL-L-A-ASPARTYL-L-PHENYLALANINE METHYL ESTER | FARMITALIA CARLO ERBA S.P.A. (IT) | 1985-10-29 | — | — | US | disclosed |