Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.52 |
| ▸ | CTSL | P07711 | 2/20 | 0.47 |
| ▸ | CTSS | P25774 | 2/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.47 |
| ▸ | CTSK | P43235 | 6/20 | 0.47 |
| ▸ | KLK7 | P49862 | 1/20 | 0.46 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30649028 | 0.97 | SYK (0.51) | SYKCTSLCTSSPSMB5CTSK | |
| SCHEMBL8592186 | 0.92 | CTSK (0.49) | SYKCTSSCTSKKLK7KLK5 | |
| SCHEMBL8592181 | 0.92 | CTSK (0.49) | SYKCTSSCTSKKLK7KLK5 | |
| SCHEMBL8671689 | 0.88 | SIRT2 (0.53) | CTSLCTSSCTSKCTSBITGB3 | |
| SCHEMBL6947000 | 0.88 | SIRT2 (0.53) | CTSLCTSSCTSKCTSBITGB3 | |
| SCHEMBL9299794 | 0.86 | SYK (0.52) | SYKCTSLCTSSCTSKKLK7 | |
| SCHEMBL2856553 | 0.85 | PPARA (0.51) | SYKCTSLCTSSCTSKKLK7 | |
| SCHEMBL6775947 | 0.85 | PPARA (0.51) | SYKCTSLCTSSCTSKKLK7 | |
| SCHEMBL26641013 | 0.84 | SIRT2 (0.55) | CTSLCTSSCTSKITGB3ITGA2B | |
| SCHEMBL26641008 | 0.84 | SIRT2 (0.55) | CTSLCTSSCTSKITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5362747-A | Promoters, inhibitors | ABBOTT LABORATORIES (US) | 1994-11-08 | — | — | US | disclosed |