Zinc Ion

Zinc Ion

SCHEMBL9302075

COc1ccc(OCCOc2cc(O)c(C(=O)[O-])c(O)c2)cc1.COc1ccc(OCCOc2cc(O)c(C(=O)[O-])c(O)c2)cc1.[Zn+2]

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFKB1 P19838 1/20 0.49
NFKB2 Q00653 1/20 0.49
RELA Q04206 1/20 0.49
SLC5A1 P13866 3/20 0.48
SLC5A2 P31639 3/20 0.48
MAPT P10636 1/20 0.46
MTNR1A P48039 1/20 0.45
MTNR1B P49286 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C19 P33261 1/20 0.45
HDAC8 Q9BY41 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
APP P05067 1/20 0.43
LMNA P02545 1/20 0.43
TP53 P04637 1/20 0.43
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Zinc Ion SCHEMBL26935 0.84 NPC1 (0.53) MAPTCYP3A4CYP2D6CYP2C19SMN1; SMN2
SCHEMBL9302084 0.83 NFKB1 (0.50) NFKB1NFKB2RELASLC5A1SLC5A2
Zinc Ion SCHEMBL8943602 0.81 MAPT (0.45) MAPTMTNR1AMTNR1BCA1CA2
SCHEMBL10595102 0.78 SLC5A1 (0.57) NFKB1NFKB2RELASLC5A1SLC5A2
SCHEMBL24845052 0.74 LTA4H (0.64) MAPTAPP
SCHEMBL29378251 0.74 PPARD (0.56) MAPTCA1CA2CYP3A4CYP2D6
SCHEMBL51025 0.74 PPARD (0.56) MAPTCA1CA2CYP3A4CYP2D6
SCHEMBL26936 0.73 PPARD (0.55) MAPTCYP3A4CYP2D6CYP2C19SMN1; SMN2
SCHEMBL17121755 0.72 MAPT (0.72) NFKB1NFKB2RELASLC5A1SLC5A2
SCHEMBL1343630 0.72 CA12 (0.65) MAPTMTNR1AMTNR1BCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6065145-A None JP disclosed
JP-H0665145-A ZINC 4-ALKOXY-2,6-DIHYDROXYBENZOATE DERIVATIVE AND RECORDING MATERIAL USING THE SAME DAINIPPON PHARMACEUT CO LTD 1994-03-08 JP disclosed