Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | UBE2M | P61081 | 1/20 | 0.43 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.43 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302313 | 0.86 | ADRA1D (0.57) | EPHX2HPGDALDH1A1ADRA1DADRA1A | |
| SCHEMBL9302740 | 0.86 | EPHX2 (0.53) | EPHX2HPGDHSD11B1MGLLKMT2A | |
| SCHEMBL9301100 | 0.85 | HPGD (0.53) | EPHX2HPGDHSD11B1MGLLKMT2A | |
| SCHEMBL9302364 | 0.84 | EPHX2 (0.46) | EPHX2HPGDHSD11B1MGLLKMT2A | |
| SCHEMBL9301240 | 0.82 | HPGD (0.49) | EPHX2HPGDHSD11B1MGLLKMT2A | |
| SCHEMBL8045655 | 0.78 | HPGD (0.48) | HPGDKMT2AALDH1A1MEN1GPBAR1 | |
| SCHEMBL8035576 | 0.76 | HPGD (0.47) | HPGDKMT2AMEN1 | |
| SCHEMBL9302070 | 0.76 | EPHX2 (0.47) | EPHX2HPGDHSD11B1MGLLKMT2A | |
| SCHEMBL9301303 | 0.75 | ADRA1D (0.56) | EPHX2HPGDHSD11B1MGLLALDH1A1 | |
| SCHEMBL9301300 | 0.75 | ADRA1D (0.60) | HPGDALDH1A1ADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | claimed |
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | disclosed |