Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | UBE2M | P61081 | 1/20 | 0.47 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302313 | 0.88 | ADRA1D (0.57) | EPHX2HPGDALDH1A1 | |
| SCHEMBL9302076 | 0.86 | EPHX2 (0.48) | EPHX2HPGDHSD11B1MGLLKMT2A | |
| SCHEMBL9301100 | 0.84 | HPGD (0.53) | EPHX2HPGDHSD11B1MGLLKMT2A | |
| SCHEMBL9302364 | 0.83 | EPHX2 (0.46) | EPHX2HPGDHSD11B1MGLLKMT2A | |
| SCHEMBL9301240 | 0.81 | HPGD (0.49) | EPHX2HPGDHSD11B1MGLLKMT2A | |
| SCHEMBL9301871 | 0.79 | CXCR4 (0.61) | KMT2AMEN1LMNA | |
| SCHEMBL9633280 | 0.78 | HPGD (0.64) | EPHX2HPGDHSD11B1MGLLKMT2A | |
| SCHEMBL8299183 | 0.76 | FAAH (0.65) | HPGDMGLLKMT2AMEN1LMNA | |
| SCHEMBL9302730 | 0.76 | EPHX2 (0.51) | EPHX2HPGDHSD11B1MGLLKMT2A | |
| SCHEMBL9301303 | 0.76 | ADRA1D (0.56) | EPHX2HPGDHSD11B1MGLLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | claimed |
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | disclosed |