SCHEMBL9301665

SCHEMBL9301665

CCN(C(=O)c1ccc(CCSc2nc3ccccc3[nH]2)cc1)C1CCCCC1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 2/20 0.53
L3MBTL1 Q9Y468 2/20 0.48
POLB P06746 2/20 0.48
APEX1 P27695 1/20 0.48
CTDSP1 Q9GZU7 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
LMNA P02545 2/20 0.45
RAB9A P51151 3/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
ALDH1A1 P00352 2/20 0.45
MAPT P10636 2/20 0.45
HDAC3 O15379 1/20 0.45
HDAC4 P56524 1/20 0.45
HDAC1 Q13547 1/20 0.45
HDAC7 Q8WUI4 1/20 0.45
HDAC2 Q92769 1/20 0.45
HDAC10 Q969S8 1/20 0.45
HDAC11 Q96DB2 1/20 0.45
HDAC8 Q9BY41 1/20 0.45
HDAC6 Q9UBN7 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9302149 0.89 AR (0.55) ARL3MBTL1POLBAPEX1CTDSP1
SCHEMBL9302077 0.83 AR (0.55) ARL3MBTL1POLBAPEX1CTDSP1
SCHEMBL9303272 0.82 HPGD (0.58) POLBLMNARAB9ASMN1; SMN2ALDH1A1
SCHEMBL9301659 0.81 KMT2A (0.46) L3MBTL1POLBAPEX1CTDSP1TDP1
SCHEMBL27203404 0.80 ATM (0.61) L3MBTL1POLBAPEX1CTDSP1TDP1
SCHEMBL29770358 0.80 ATM (0.61) L3MBTL1POLBAPEX1CTDSP1TDP1
SCHEMBL9302594 0.77 AR (0.55) ARL3MBTL1POLBAPEX1CTDSP1
SCHEMBL10722280 0.72 HSD11B1 (0.70) L3MBTL1LMNARAB9ANPC1MEN1
SCHEMBL4139952 0.71 L3MBTL1 (0.62) L3MBTL1LMNAALDH1A1MAPTMEN1
SCHEMBL9302074 0.70 PTAFR (0.46) L3MBTL1POLBAPEX1CTDSP1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0468971-A1 NOVEL BENZIMIDAZOLE DERIVATIVES BRITISH BIO-TECHNOLOGY LIMITED (GB) 1992-02-05 EP claimed
WO-1990009997-A1 NOVEL BENZIMIDAZOLE DERIVATIVES BRITISH BIO-TECHNOLOGY LIMITED (GB) 1990-09-07 WO claimed
US-5314880-A Platelet activating factor antagonist BRITISH BIO-TECHNOLOGY LIMITED (GB) 1994-05-24 US disclosed
EP-0468971-A1 NOVEL BENZIMIDAZOLE DERIVATIVES BRITISH BIO-TECHNOLOGY LIMITED (GB) 1992-02-05 EP disclosed
WO-1990009997-A1 NOVEL BENZIMIDAZOLE DERIVATIVES BRITISH BIO-TECHNOLOGY LIMITED (GB) 1990-09-07 WO disclosed