Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7519212 | 0.87 | TSHR (0.35) | TSHR | |
| SCHEMBL28555596 | 0.84 | TSHR (0.41) | TSHR | |
| SCHEMBL16537252 | 0.75 | TSHR (0.39) | TSHR | |
| SCHEMBL9767763 | 0.75 | TSHR (0.34) | TSHR | |
| SCHEMBL2744042 | 0.75 | TSHR (0.34) | TSHR | |
| SCHEMBL9292223 | 0.74 | TSHR (0.32) | TSHR | |
| SCHEMBL9637767 | 0.73 | TSHR (0.43) | TSHR | |
| SCHEMBL2744226 | 0.72 | TSHR (0.39) | TSHR | |
| SCHEMBL16536505 | 0.71 | TSHR (0.40) | TSHR | |
| SCHEMBL435743 | 0.71 | MAPT (0.36) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317297-A1 | METHODS AND COMPOSITION OF A DENTAL MODEL FOR THE MANUFACTURE OF ORTHODONTIC APPLIANCES WITHOUT THE USE OF SEPARATOR | STRUCTO PTE LTD (SG) | 2021-10-14 | — | — | US | disclosed |
| CN-102690419-B | Silicon-containing prepolymer and silicone hydrogel biomaterial containing same | ZHAN QIANQING | 2014-05-07 | — | — | CN | disclosed |
| CN-102690419-A | Silicon-containing prepolymer and silicone hydrogel biomaterial containing same | QIANQING ZHAN | 2012-09-26 | — | — | CN | disclosed |
| US-5371147-A | Silicone-containing acrylic star polymers, block copolymers and macromonomers | PERMEABLE TECHNOLOGIES, INC. (US) | 1994-12-06 | — | — | US | disclosed |
| US-5331067-A | Acrylic polymers containing trimethylsiloxy groups | PERMEABLE TECHNOLOGIES, INC. (US) | 1994-07-19 | — | — | US | disclosed |
| US-5314961-A | Acrylic-silicone polymers | PERMEABLE TECHNOLOGIES, INC. (US) | 1994-05-24 | — | — | US | disclosed |
| US-5314960-A | Silicone-containing polymers, oxygen permeable hydrophilic contact lenses and methods for making these lenses and treating patients with visual impairment | PERMEABLE TECHNOLOGIES, INC. (US) | 1994-05-24 | — | — | US | disclosed |
| US-5244981-A | Acrylic polymers with pendant silicon containing groups, macromonomers, star polymers | PERMEABLE TECHNOLOGIES, INC. (US) | 1993-09-14 | — | — | US | disclosed |
| EP-0552306-A1 | NOVEL SILICONE-CONTAINING POLYMERS AND OXYGEN PERMEABLE HYDROPHILIC CONTACT LENSES THEREFROM | PERMEABLE TECHNOLOGIES, INC. (US) | 1993-07-28 | — | — | EP | disclosed |
| WO-1992007013-A1 | NOVEL SILICONE-CONTAINING POLYMERS AND OXYGEN PERMEABLE HYDROPHILIC CONTACT LENSES THEREFROM | PERMEABLE TECHNOLOGIES, INC. (US) | 1992-04-30 | — | — | WO | disclosed |
| EP-0452098-A2 | Silicone-containing block copolymers and macromonomers | E.I. du Pont de Nemours and Company (US) | 1991-10-16 | — | — | EP | disclosed |
| EP-0452097-A2 | Silicone containing acrylic star polymers | E.I. du Pont de Nemours and Company (US) | 1991-10-16 | — | — | EP | disclosed |
| US-5057578-A | Contact lenses | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-10-15 | — | — | US | disclosed |
| US-RE31406-E | POLYSILOXANYLALKYL ACRYLATE AND ALKYL ACRYLATE COPOLYMER | SYNTEX (U.S.A.) INC. (US) | 1983-10-04 | — | — | US | disclosed |
| EP-0075004-A1 | SILICONE METHACRYLATE HYDROGELS FOR CONTACT LENSES | McCARRY, John D. (US) | 1983-03-30 | — | — | EP | disclosed |
| WO-1982003397-A1 | SILICONE METHACRYLATE HYDROGELS FOR CONTACT LENSES | MCCARRY JOHN D (US) | 1982-10-14 | — | — | WO | disclosed |
| US-4120570-A | POLYSILOXANYLALKYL ACRYLATE OR METHACRYLATE AND AN ALKYL ACRYLATE OR METHACRYLATE | SYNTEX (U.S.A.) INC. (US) | 1978-10-17 | — | — | US | disclosed |