Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28555596 | 0.86 | TSHR (0.41) | TSHR | |
| SCHEMBL7519212 | 0.78 | TSHR (0.35) | TSHR | |
| SCHEMBL16537252 | 0.77 | TSHR (0.39) | TSHR | |
| SCHEMBL9302195 | 0.75 | TSHR (0.33) | TSHR | |
| SCHEMBL9637767 | 0.74 | TSHR (0.43) | TSHR | |
| SCHEMBL2744277 | 0.73 | TSHR (0.34) | TSHR | |
| SCHEMBL16536505 | 0.72 | TSHR (0.40) | TSHR | |
| SCHEMBL435743 | 0.72 | MAPT (0.36) | TSHR | |
| SCHEMBL28024178 | 0.72 | TSHR (0.38) | TSHR | |
| SCHEMBL1899461 | 0.70 | TSHR (0.34) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102690419-B | Silicon-containing prepolymer and silicone hydrogel biomaterial containing same | ZHAN QIANQING | 2014-05-07 | — | — | CN | disclosed |
| CN-102690419-A | Silicon-containing prepolymer and silicone hydrogel biomaterial containing same | QIANQING ZHAN | 2012-09-26 | — | — | CN | disclosed |
| EP-0452097-A2 | Silicone containing acrylic star polymers | E.I. du Pont de Nemours and Company (US) | 1991-10-16 | — | — | EP | disclosed |
| US-5057578-A | Contact lenses | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-10-15 | — | — | US | disclosed |
| US-RE31406-E | POLYSILOXANYLALKYL ACRYLATE AND ALKYL ACRYLATE COPOLYMER | SYNTEX (U.S.A.) INC. (US) | 1983-10-04 | — | — | US | disclosed |
| EP-0075004-A1 | SILICONE METHACRYLATE HYDROGELS FOR CONTACT LENSES | McCARRY, John D. (US) | 1983-03-30 | — | — | EP | disclosed |
| WO-1982003397-A1 | SILICONE METHACRYLATE HYDROGELS FOR CONTACT LENSES | MCCARRY JOHN D (US) | 1982-10-14 | — | — | WO | disclosed |
| US-4120570-A | POLYSILOXANYLALKYL ACRYLATE OR METHACRYLATE AND AN ALKYL ACRYLATE OR METHACRYLATE | SYNTEX (U.S.A.) INC. (US) | 1978-10-17 | — | — | US | disclosed |