Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 3/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.38 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8921802 | 1.00 | KDM4E (0.40) | KDM4EALDH1A1HPGDHTTL3MBTL1 | |
| SCHEMBL9866799 | 1.00 | KDM4E (0.40) | KDM4EALDH1A1HPGDHTTL3MBTL1 | |
| SCHEMBL8879728 | 0.83 | — | — | |
| SCHEMBL9506148 | 0.82 | CYP2D6 (0.57) | KDM4EALDH1A1HPGDHTTL3MBTL1 | |
| SCHEMBL9506174 | 0.82 | CYP2D6 (0.57) | KDM4EALDH1A1HPGDHTTL3MBTL1 | |
| SCHEMBL9403655 | 0.82 | SOAT1 (0.40) | KDM4EALDH1A1HPGDHTTL3MBTL1 | |
| SCHEMBL9062136 | 0.81 | NPC1 (0.58) | KDM4EALDH1A1HPGDHTTL3MBTL1 | |
| SCHEMBL9801755 | 0.81 | NPC1 (0.58) | KDM4EALDH1A1HPGDHTTL3MBTL1 | |
| SCHEMBL8919072 | 0.81 | NR5A1 (0.57) | KDM4EALDH1A1HPGDHTTL3MBTL1 | |
| SCHEMBL8034268 | 0.81 | NR5A1 (0.57) | KDM4EALDH1A1HPGDHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286409-A | High contrast, low melting point and short switching times | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-02-15 | — | — | US | disclosed |
| US-4988459-A | Electrooptic switches or display | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-01-29 | — | — | US | disclosed |