Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.66 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.58 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7015366 | 0.91 | PPARG (0.56) | PPARG | |
| SCHEMBL7145725 | 0.86 | AGTR2 (0.57) | AGTR1AGTR2 | |
| SCHEMBL12096488 | 0.85 | AGTR1 (0.69) | PPARGAGTR1AGTR2 | |
| SCHEMBL8543694 | 0.85 | AGTR2 (0.80) | PPARGAGTR1AGTR2 | |
| SCHEMBL7017631 | 0.84 | — | — | |
| SCHEMBL7014870 | 0.84 | PPARG (0.56) | PPARG | |
| SCHEMBL9485211 | 0.84 | PPARG (0.49) | PPARG | |
| SCHEMBL7014033 | 0.80 | AGTR2 (0.72) | PPARGAGTR1AGTR2 | |
| SCHEMBL30206881 | 0.80 | AGTR1 (0.63) | PPARGAGTR1AGTR2 | |
| SCHEMBL9193754 | 0.80 | PPARG (0.60) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354766-A | 2-Ethoxy-1-((2'(2,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl) biphenyl-4-yl)methyl)benzimidazole-7-carboxylic acid; hypotensive agents; CNS activity | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-10-11 | — | — | US | disclosed |