Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR3 | O60755 | 2/20 | 0.67 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | PTAFR | P25105 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | TNF | P01375 | 2/20 | 0.54 |
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.52 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.48 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.48 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.48 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.48 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.48 |
| ▸ | TSPO | P30536 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302639 | 0.93 | PTAFR (0.64) | GALR3NR2F2RAB9APTAFRTSHR | |
| SCHEMBL9302593 | 0.92 | PTAFR (0.62) | GALR3NR2F2RAB9APTAFRTSHR | |
| SCHEMBL9302731 | 0.90 | GALR3 (0.68) | GALR3NR2F2RAB9APTAFRTSHR | |
| SCHEMBL9303024 | 0.90 | PTAFR (0.58) | GALR3NR2F2RAB9APTAFRTSHR | |
| SCHEMBL9302637 | 0.87 | PTAFR (0.57) | GALR3NR2F2RAB9APTAFRTSHR | |
| Chlormidazole SCHEMBL148113 | 0.82 | GALR3 (1.00) | GALR3NR2F2RAB9ATSHRTNF | |
| Chlormidazole SCHEMBL30402878 | 0.82 | GALR3 (1.00) | GALR3NR2F2RAB9ATSHRTNF | |
| SCHEMBL9302023 | 0.81 | PTAFR (0.66) | GALR3NR2F2RAB9APTAFRTNF | |
| Chlormidazole SCHEMBL364033 | 0.81 | GALR3 (0.97) | GALR3NR2F2RAB9ATSHRTNF | |
| SCHEMBL9303788 | 0.80 | TNF (0.61) | GALR3NR2F2RAB9APTAFRTNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | claimed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | claimed |
| US-5314880-A | Platelet activating factor antagonist | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-05-24 | — | — | US | disclosed |
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | disclosed |