Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 2/20 | 0.57 |
| ▸ | TNF | P01375 | 1/20 | 0.52 |
| ▸ | GALR3 | O60755 | 3/20 | 0.52 |
| ▸ | NR2F2 | P24468 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | VDR | P11473 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302639 | 0.89 | PTAFR (0.64) | PTAFRTNFGALR3NR2F2RAB9A | |
| SCHEMBL9302593 | 0.88 | PTAFR (0.62) | PTAFRTNFGALR3NR2F2RAB9A | |
| SCHEMBL9302294 | 0.87 | GALR3 (0.67) | PTAFRTNFGALR3NR2F2RAB9A | |
| SCHEMBL9302731 | 0.86 | GALR3 (0.68) | PTAFRTNFGALR3NR2F2RAB9A | |
| SCHEMBL9303024 | 0.84 | PTAFR (0.58) | PTAFRTNFGALR3NR2F2RAB9A | |
| SCHEMBL10474692 | 0.81 | PTAFR (0.50) | PTAFRTNFGALR3NR2F2RAB9A | |
| SCHEMBL9302023 | 0.77 | PTAFR (0.66) | PTAFRTNFGALR3NR2F2RAB9A | |
| SCHEMBL9303788 | 0.77 | TNF (0.61) | PTAFRTNFGALR3NR2F2RAB9A | |
| SCHEMBL14470052 | 0.77 | POLB (0.67) | GALR3NR2F2RAB9ALMNAHTT | |
| SCHEMBL9300543 | 0.76 | TNF (0.67) | PTAFRTNFGALR3NR2F2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | claimed |
| US-5314880-A | Platelet activating factor antagonist | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-05-24 | — | — | US | disclosed |