Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 2/20 | 0.62 |
| ▸ | TNF | P01375 | 1/20 | 0.61 |
| ▸ | GALR3 | O60755 | 3/20 | 0.57 |
| ▸ | NR2F2 | P24468 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302639 | 0.97 | PTAFR (0.64) | PTAFRTNFGALR3NR2F2RAB9A | |
| SCHEMBL9302294 | 0.92 | GALR3 (0.67) | PTAFRTNFGALR3NR2F2RAB9A | |
| SCHEMBL9302731 | 0.91 | GALR3 (0.68) | PTAFRTNFGALR3NR2F2RAB9A | |
| SCHEMBL9302637 | 0.88 | PTAFR (0.57) | PTAFRTNFGALR3NR2F2RAB9A | |
| SCHEMBL9303024 | 0.86 | PTAFR (0.58) | PTAFRTNFGALR3NR2F2RAB9A | |
| SCHEMBL9302023 | 0.84 | PTAFR (0.66) | PTAFRTNFGALR3NR2F2RAB9A | |
| SCHEMBL9303788 | 0.83 | TNF (0.61) | PTAFRTNFGALR3NR2F2RAB9A | |
| SCHEMBL9302841 | 0.81 | CNR2 (0.59) | PTAFRTNFGALR3NR2F2RAB9A | |
| SCHEMBL10474692 | 0.81 | PTAFR (0.50) | PTAFRTNFGALR3NR2F2RAB9A | |
| SCHEMBL9299088 | 0.81 | PTAFR (0.62) | PTAFRTNFGALR3NR2F2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | claimed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | claimed |
| US-5314880-A | Platelet activating factor antagonist | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-05-24 | — | — | US | disclosed |
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | disclosed |