Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | LSS | P48449 | 1/20 | 0.44 |
| ▸ | PTAFR | P25105 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 3/20 | 0.42 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303481 | 0.87 | ALDH1A1 (0.50) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL9302837 | 0.87 | ALDH1A1 (0.59) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL9302099 | 0.86 | ALDH1A1 (0.44) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL9302515 | 0.77 | ALDH1A1 (0.44) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL9301340 | 0.75 | ALDH1A1 (0.55) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL12188831 | 0.71 | HTR2A (0.72) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL9302302 | 0.71 | CXCR4 (0.48) | ALDH1A1MEN1KMT2ALMNANAMPT | |
| SCHEMBL10474862 | 0.71 | PTAFR (0.50) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL9304267 | 0.71 | ALDH1A1 (0.49) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL400238 | 0.70 | ALDH1A1 (0.65) | ALDH1A1KDM4EMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | claimed |
| US-5314880-A | Platelet activating factor antagonist | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-05-24 | — | — | US | disclosed |
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | disclosed |