Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PTAFR | P25105 | 1/20 | 0.46 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 3/20 | 0.44 |
| ▸ | HTR2C | P28335 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302837 | 0.88 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL9302513 | 0.87 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL9302099 | 0.85 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL10474862 | 0.81 | PTAFR (0.50) | ALDH1A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL9302515 | 0.78 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL9301340 | 0.76 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL12188831 | 0.75 | HTR2A (0.72) | ALDH1A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL400238 | 0.73 | ALDH1A1 (0.65) | ALDH1A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL9303072 | 0.73 | ALDH1A1 (0.73) | ALDH1A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL13176112 | 0.72 | HTR2A (0.73) | ALDH1A1MEN1KMT2AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5314880-A | Platelet activating factor antagonist | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-05-24 | — | — | US | disclosed |
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | disclosed |