Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18554566 | 0.98 | TSHR (0.63) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL9122872 | 0.95 | TSHR (0.62) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL374776 | 0.95 | TSHR (0.57) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL14330279 | 0.90 | TSHR (0.61) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL332090 | 0.89 | TSHR (0.59) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL3477474 | 0.89 | TSHR (0.55) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL9302488 | 0.87 | TSHR (0.50) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL7761501 | 0.87 | TSHR (0.62) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL9764152 | 0.87 | TSHR (0.52) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL14175495 | 0.86 | TSHR (0.55) | TSHRALDH1A1CYP3A4HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11427666-B2 | Silicone-containing acrylic polymers for transdermal drug delivery compositions | NOVEN PHARMACEUTICALS, INC. (US) | 2022-08-30 | — | — | US | disclosed |
| US-20200277424-A1 | SILICONE-CONTAINING ACRYLIC POLYMERS FOR TRANSDERMAL DRUG DELIVERY COMPOSITIONS | NOVEN PHARMACEUTICALS, INC. (US) | 2020-09-03 | — | — | US | disclosed |
| CN-110023067-A | The method for manufacturing haptic lens | 诺华股份有限公司 | 2019-07-16 | — | — | CN | disclosed |
| EP-3179989-B1 | SILICONE-CONTAINING ACRYLIC POLYMERS FOR TRANSDERMAL DRUG DELIVERY COMPOSITIONS | NOVEN PHARMA (US) | 2019-06-12 | — | — | EP | disclosed |
| CN-109803815-A | The method for manufacturing haptic lens | 诺华股份有限公司 | 2019-05-24 | — | — | CN | disclosed |
| US-20160030362-A1 | SILICONE-CONTAINING ACRYLIC POLYMERS FOR TRANSDERMAL DRUG DELIVERY COMPOSITIONS | NOVEN PHARMACEUTICALS, INC. (US) | 2016-02-04 | — | — | US | disclosed |
| US-5376378-A | Transdermal drug delivery | CIBA-GEIGY CORP. (US) | 1994-12-27 | — | — | US | disclosed |
| US-5288827-A | Drug selivery | CIBA-GEIGY CORPORATION (US) | 1994-02-22 | — | — | US | disclosed |