Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 6/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7018778 | 0.82 | AGTR1 (0.36) | AGTR1TP53AGTR2RXFP1 | |
| SCHEMBL7018118 | 0.79 | TP53 (0.37) | AGTR1TP53RXFP1 | |
| SCHEMBL9032306 | 0.79 | PPARG (0.42) | AGTR1AGTR2 | |
| SCHEMBL7016159 | 0.79 | AGTR1 (0.40) | AGTR1TP53AGTR2 | |
| SCHEMBL9032973 | 0.78 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL7016402 | 0.78 | AGTR1 (0.39) | AGTR1TP53 | |
| SCHEMBL7012387 | 0.78 | AGTR1 (0.38) | AGTR1AGTR2 | |
| SCHEMBL7016142 | 0.78 | AGTR1 (0.39) | AGTR1AGTR2 | |
| SCHEMBL683666 | 0.76 | PPARG (0.50) | AGTR1AGTR2 | |
| SCHEMBL7012900 | 0.76 | AGTR1 (0.38) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354766-A | 2-Ethoxy-1-((2'(2,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl) biphenyl-4-yl)methyl)benzimidazole-7-carboxylic acid; hypotensive agents; CNS activity | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-10-11 | — | — | US | disclosed |