Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TYR | P14679 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | ESRRG | P62508 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.46 |
| ▸ | ABAT | P80404 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1332508 | 0.79 | CYP2C9 (0.41) | ESR1ESR2CYP3A4TSHRALDH1A1 | |
| SCHEMBL2172033 | 0.77 | MEN1 (0.52) | CYP3A4LMNAHSD17B10TSHRMAPT | |
| SCHEMBL3825948 | 0.77 | KCNN4 (0.46) | CYP3A4LMNAMAPTMEN1NPC1 | |
| SCHEMBL8943820 | 0.73 | ESR1 (0.46) | ESR1ESR2CYP3A4LMNATYR | |
| SCHEMBL9153305 | 0.72 | ESR1 (0.44) | ESR1ESR2CYP3A4LMNATYR | |
| SCHEMBL21701236 | 0.72 | ESR1 (0.56) | ESR1ESR2CYP3A4LMNATYR | |
| SCHEMBL7753917 | 0.72 | ESR1 (0.56) | ESR1ESR2CYP3A4LMNATYR | |
| SCHEMBL29004385 | 0.72 | ESR1 (0.46) | ESR1ESR2CYP3A4LMNATYR | |
| SCHEMBL15419956 | 0.72 | ESR2 (0.54) | ESR1ESR2CYP3A4LMNATYR | |
| SCHEMBL3451789 | 0.71 | ESR1 (0.55) | ESR1ESR2CYP3A4LMNATYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292945-A | Process for preparing α-chloro-α-oximino-4-hydroxyacetophenone | HOECHST CELANESE CORPORATION (US) | 1994-03-08 | — | — | US | disclosed |
| EP-0545682-A2 | Process for preparing alpha-chloro-alpha-oximino-4-hydroxyacetophenone | HOECHST CELANESE CORPORATION (US) | 1993-06-09 | — | — | EP | disclosed |