Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GRM8 | O00222 | 1/20 | 0.40 |
| ▸ | GRM6 | O15303 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ACP1 | P24666 | 1/20 | 0.38 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.38 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.38 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylglycine SCHEMBL19305461 | 0.83 | DPP7 (0.46) | SRCCYP2D6MEN1CYP2C9CYP2C19 | |
| Trifluoromethanesulfonic Acid SCHEMBL8215497 | 0.83 | SRC (0.44) | SRCCYP2D6LMNAMAPK1ACP1 | |
| Phenylglycine SCHEMBL71958 | 0.82 | CYP2D6 (0.56) | SRCCYP2D6MEN1CYP2C9CYP2C19 | |
| Phenylglycine SCHEMBL30559595 | 0.82 | CYP2D6 (0.56) | SRCCYP2D6MEN1CYP2C9CYP2C19 | |
| Phenylglycine SCHEMBL27801493 | 0.82 | CYP2D6 (0.56) | SRCCYP2D6MEN1CYP2C9CYP2C19 | |
| Phenylglycine SCHEMBL11576917 | 0.82 | CYP2D6 (0.56) | SRCCYP2D6MEN1CYP2C9CYP2C19 | |
| Phenylglycine SCHEMBL157180 | 0.82 | CYP2D6 (0.56) | SRCCYP2D6MEN1CYP2C9CYP2C19 | |
| Phenylglycine SCHEMBL31402004 | 0.82 | CYP2D6 (0.56) | SRCCYP2D6MEN1CYP2C9CYP2C19 | |
| Phenylglycine SCHEMBL159420 | 0.82 | CYP2D6 (0.56) | SRCCYP2D6MEN1CYP2C9CYP2C19 | |
| Phenylglycine SCHEMBL6718142 | 0.80 | CYP2D6 (0.54) | SRCCYP2D6MEN1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5338868-A | Reacting glycine derivative with trifluoro methane sulfonic acid derivative at low temperature | CHINOIN GYOGYSZER- ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1994-08-16 | — | — | US | disclosed |