SCHEMBL9302798

SCHEMBL9302798

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)Cl.FC(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
KDM4E B2RXH2 1/20 0.32
TSHR P16473 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11692094 0.92 KDM4E (0.36) KDM4ETSHRTDP1
SCHEMBL6397394 0.92 KDM4E (0.36) KDM4ETSHRTDP1
SCHEMBL817265 0.89 LMNA (0.40) LMNAKDM4ETSHRTDP1
SCHEMBL815543 0.89 LMNA (0.40) LMNAKDM4ETSHRTDP1
SCHEMBL506811 0.89 LMNA (0.40) LMNAKDM4ETSHRTDP1
SCHEMBL735601 0.89 LMNA (0.40) LMNAKDM4ETSHRTDP1
SCHEMBL506073 0.89 LMNA (0.40) LMNAKDM4ETSHRTDP1
SCHEMBL8675609 0.89 KDM4E (0.37) KDM4ETSHRTDP1
SCHEMBL817697 0.89 LMNA (0.40) LMNAKDM4ETSHRTDP1
SCHEMBL816970 0.89 LMNA (0.40) LMNAKDM4ETSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5295953-A Method and apparatus for extracorporeal separation of fluorochemicals from whole blood of a patient HEMAGEN/PFC (US) 1994-03-22 US claimed
WO-1993024158-A1 METHOD AND APPARATUS FOR EXTRACORPOREAL SEPARATION OF FLUOROCHEMICALS FROM WHOLE BLOOD OF A PATIENT HEMAGEN/PFC (US) 1993-12-09 WO claimed