SCHEMBL9302882

SCHEMBL9302882

[CH2]NC(=O)C(N)CCC(N)=O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BLM P54132 2/20 0.56
ALOX15 P16050 1/20 0.56
PMP22 Q01453 1/20 0.56
KMT2A Q03164 1/20 0.56
DPP4 P27487 3/20 0.53
DPP8 Q6V1X1 3/20 0.53
DPP9 Q86TI2 3/20 0.53
GRM8 O00222 1/20 0.37
GRM6 O15303 1/20 0.37
GRIN2D O15399 1/20 0.37
GRIN3B O60391 1/20 0.37
GSR P00390 1/20 0.37
CYP1A2 P05177 1/20 0.37
GRIK1 P39086 1/20 0.37
GRM5 P41594 1/20 0.37
GRIA1 P42261 1/20 0.37
GRIA2 P42262 1/20 0.37
GRIA3 P42263 1/20 0.37
SLC1A3 P43003 1/20 0.37
SLC1A2 P43004 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9304411 0.83 GRM8 (0.58) BLMALOX15PMP22KMT2ADPP4
SCHEMBL8773315 0.82 BLM (0.60) BLMALOX15PMP22KMT2ADPP4
SCHEMBL4321248 0.80 BLM (0.58) BLMALOX15PMP22KMT2ADPP4
SCHEMBL21447963 0.80 BLM (0.58) BLMALOX15PMP22KMT2ADPP4
SCHEMBL288407 0.80 BLM (0.58) BLMALOX15PMP22KMT2ADPP4
SCHEMBL11478144 0.80 BLM (0.58) BLMALOX15PMP22KMT2ADPP4
SCHEMBL29833669 0.80 BLM (0.58) BLMALOX15PMP22KMT2ADPP4
SCHEMBL25326982 0.79 BLM (0.52) BLMALOX15PMP22KMT2ADPP4
SCHEMBL92829 0.78 BLM (0.56) BLMALOX15PMP22KMT2ADPP4
SCHEMBL5574087 0.78 BLM (0.56) BLMALOX15PMP22KMT2ADPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5290794-A Storage stable compositions WARNER LAMBERT CO. (US) 1994-03-01 US claimed
US-5290794-A Storage stable compositions WARNER LAMBERT CO. (US) 1994-03-01 US disclosed