SCHEMBL11478144

SCHEMBL11478144

NNC(=O)C(N)CCC(N)=O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BLM P54132 2/20 0.58
ALOX15 P16050 1/20 0.58
PMP22 Q01453 1/20 0.58
KMT2A Q03164 1/20 0.58
DPP4 P27487 3/20 0.55
DPP8 Q6V1X1 3/20 0.55
DPP9 Q86TI2 3/20 0.55
HIF1A Q16665 1/20 0.39
CYP1A2 P05177 2/20 0.38
GRM8 O00222 1/20 0.38
GRM6 O15303 1/20 0.38
GRIN2D O15399 1/20 0.38
GRIN3B O60391 1/20 0.38
GSR P00390 1/20 0.38
GRIK1 P39086 1/20 0.38
GRM5 P41594 1/20 0.38
GRIA1 P42261 1/20 0.38
GRIA2 P42262 1/20 0.38
GRIA3 P42263 1/20 0.38
SLC1A3 P43003 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL288407 1.00 BLM (0.58) BLMALOX15PMP22KMT2ADPP4
SCHEMBL29833669 1.00 BLM (0.58) BLMALOX15PMP22KMT2ADPP4
SCHEMBL8773315 0.84 BLM (0.60) BLMALOX15PMP22KMT2ADPP4
SCHEMBL4629339 0.83 DPP4 (0.40) BLMALOX15PMP22KMT2ADPP4
SCHEMBL709482 0.82 GRM8 (0.60) BLMALOX15PMP22KMT2ADPP4
SCHEMBL1534041 0.82 CTSD (0.44) BLMALOX15PMP22KMT2ADPP4
SCHEMBL709483 0.82 GRM8 (0.60) BLMALOX15PMP22KMT2ADPP4
SCHEMBL1534035 0.82 CTSD (0.44) BLMALOX15PMP22KMT2ADPP4
SCHEMBL308629 0.82 CTSD (0.44) BLMALOX15PMP22KMT2ADPP4
SCHEMBL21447963 0.82 BLM (0.58) BLMALOX15PMP22KMT2ADPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112538152-B Waterborne polyurethane-polyurea dispersion and preparation method and application thereof 万华化学集团股份有限公司 2022-09-20 CN claimed
CN-112538152-A Waterborne polyurethane-polyurea dispersion and preparation method and application thereof 万华化学集团股份有限公司 2021-03-23 CN claimed
WO-2023173132-A1 ANTI-GLP1R ANTIBODY-DRUG CONJUGATES COMPRISING GLP1 PEPTIDOMIMETICS AND USES THEREOF REGENERON PHARMACEUTICALS, INC. (US) 2023-09-14 WO disclosed
CN-112538152-B Waterborne polyurethane-polyurea dispersion and preparation method and application thereof 万华化学集团股份有限公司 2022-09-20 CN disclosed
CN-112538152-A Waterborne polyurethane-polyurea dispersion and preparation method and application thereof 万华化学集团股份有限公司 2021-03-23 CN disclosed
US-4219650-A REACTION OF L-GLUTAMIC ACID ESTER METAL COMPLEX WITH A DIAMINE CIBA-GEIGY CORPORATION (US) 1980-08-26 US disclosed