Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | CNR2 | P34972 | 9/20 | 0.60 |
| ▸ | CNR1 | P21554 | 3/20 | 0.57 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14470257 | 0.93 | ALDH1A1 (0.69) | ALDH1A1LMNACNR2CXCR4MAPT | |
| SCHEMBL31612502 | 0.91 | MAPT (0.63) | ALDH1A1LMNACNR2CNR1CXCR4 | |
| SCHEMBL407669 | 0.89 | ALDH1A1 (0.73) | NR1H3ALDH1A1LMNACXCR4MAPT | |
| SCHEMBL9305267 | 0.85 | NR1H3 (0.59) | NR1H3ALDH1A1LMNACNR2CXCR4 | |
| SCHEMBL4072202 | 0.85 | NR1H3 (0.63) | NR1H3ALDH1A1LMNACXCR4MAPT | |
| SCHEMBL27864280 | 0.84 | CNR2 (0.58) | CNR2CNR1TSHRHTTTAS2R14 | |
| SCHEMBL14285692 | 0.83 | TAS2R14 (0.64) | NR1H3ALDH1A1LMNACNR2CNR1 | |
| SCHEMBL20387915 | 0.82 | CNR2 (0.70) | ALDH1A1LMNACNR2CNR1MAPT | |
| SCHEMBL18773879 | 0.82 | ALDH1A1 (0.57) | ALDH1A1LMNACNR2CNR1MAPT | |
| SCHEMBL4068031 | 0.82 | NR1H3 (0.57) | NR1H3ALDH1A1LMNACNR2CXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5314880-A | Platelet activating factor antagonist | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-05-24 | — | — | US | disclosed |
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | disclosed |