Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 19/20 | 0.66 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.66 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.53 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8799890 | 0.83 | ALOX5 (0.70) | ALOX5HDAC6CYSLTR1 | |
| SCHEMBL8965126 | 0.83 | ALOX5 (0.70) | ALOX5HDAC6CYSLTR1 | |
| SCHEMBL9018914 | 0.83 | ALOX5 (0.69) | ALOX5HDAC6CYSLTR2CYSLTR1 | |
| SCHEMBL8801108 | 0.83 | ALOX5 (0.69) | ALOX5HDAC6 | |
| SCHEMBL10521151 | 0.83 | ALOX5 (0.69) | ALOX5HDAC6 | |
| SCHEMBL7234994 | 0.82 | ALOX5 (0.70) | ALOX5HDAC6 | |
| SCHEMBL8799865 | 0.82 | ALOX5 (0.73) | ALOX5HDAC6 | |
| SCHEMBL10520188 | 0.82 | ALOX5 (0.70) | ALOX5HDAC6 | |
| SCHEMBL8965421 | 0.82 | ALOX5 (0.73) | ALOX5HDAC6 | |
| SCHEMBL8965314 | 0.81 | ALOX5 (0.66) | ALOX5HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310744-A | Antiinflammatory | BAYER AKTIENGESELLSCHAFT (DE) | 1994-05-10 | — | — | US | disclosed |
| US-5288733-A | Quinolylmethoxyphenylacetic acid acylamides and ureas | BAYER AKTIENGESELLSCHAFT (DE) | 1994-02-22 | — | — | US | disclosed |
| EP-0545170-A1 | Quinolylmethoxyphenylacetamides | BAYER AG (DE) | 1993-06-09 | — | — | EP | disclosed |
| EP-0545171-A1 | Quinolylmethoxyphenyl acetic acid acylamides and ureas | BAYER AG (DE) | 1993-06-09 | — | — | EP | disclosed |