SCHEMBL9303047

SCHEMBL9303047

O=C(CO)OC(=O)CCl.[NaH]

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9151154 0.97
SCHEMBL27705406 0.88 TSHR (0.41) TSHRALDH1A1
SCHEMBL27713192 0.88 TSHR (0.41) TSHRALDH1A1
SCHEMBL16026 0.85
SCHEMBL2131209 0.85 ALDH1A1 (0.40) TSHRALDH1A1
SCHEMBL132924 0.82
SCHEMBL2750422 0.77 ALDH1A1 (0.48) TSHRALDH1A1
Sulfur Dioxide SCHEMBL28841867 0.77 TSHR (0.37) TSHRALDH1A1
SCHEMBL28652300 0.74
SCHEMBL799950 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5326887-A Reacting ester of alpha hydroxy acid oligomer over fixed bed catalyst E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-07-05 US disclosed
WO-1992015572-A1 PROCESS FOR THE PREPARATION OF 1,4-DIOXANE-2,5-DIONES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-09-17 WO disclosed