Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303074 | 1.00 | ELANE (0.46) | ELANEATML3MBTL1CYP19A1LMNA | |
| SCHEMBL9710081 | 0.92 | ELANE (0.41) | ELANEATML3MBTL1CYP19A1LMNA | |
| SCHEMBL28238266 | 0.88 | ELANE (0.51) | ELANEATML3MBTL1CYP19A1LMNA | |
| SCHEMBL28327575 | 0.85 | PRSS1 (0.43) | ELANEATML3MBTL1CYP19A1GAA | |
| SCHEMBL9305068 | 0.81 | ALDH1A1 (0.50) | ATML3MBTL1CYP19A1LMNAPRSS1 | |
| SCHEMBL9305059 | 0.81 | ALDH1A1 (0.50) | ATML3MBTL1CYP19A1LMNAPRSS1 | |
| SCHEMBL3740302 | 0.81 | ELANE (0.55) | ELANEATML3MBTL1LMNAGAA | |
| SCHEMBL3744640 | 0.81 | ELANE (0.55) | ELANEATML3MBTL1LMNAGAA | |
| SCHEMBL197674 | 0.81 | ELANE (0.55) | ELANEATML3MBTL1LMNAGAA | |
| SCHEMBL2907355 | 0.80 | ALDH1A1 (0.50) | ELANEATML3MBTL1CYP19A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371001-A | Transesterification in the presence of carboxy-esterases or carboxyamidases | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-12-06 | — | — | US | disclosed |
| US-5326887-A | Reacting ester of alpha hydroxy acid oligomer over fixed bed catalyst | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-07-05 | — | — | US | disclosed |
| US-5254718-A | Using enzyme catalyst; simplified separation, purification | E. I. DU PONT DE NEMOURS & COMPANY (US) | 1993-10-19 | — | — | US | disclosed |
| WO-1992015572-A1 | PROCESS FOR THE PREPARATION OF 1,4-DIOXANE-2,5-DIONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-09-17 | — | — | WO | disclosed |