Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303074 | 0.92 | ELANE (0.46) | ELANEATML3MBTL1CYP19A1GAA | |
| SCHEMBL9303071 | 0.92 | ELANE (0.46) | ELANEATML3MBTL1CYP19A1GAA | |
| SCHEMBL28238266 | 0.81 | ELANE (0.51) | ELANEATML3MBTL1CYP19A1GAA | |
| SCHEMBL142256 | 0.80 | CYP19A1 (0.52) | ELANEATML3MBTL1CYP19A1PRSS1 | |
| Hydrochloric Acid SCHEMBL11284785 | 0.79 | CYP19A1 (0.50) | ELANEATML3MBTL1CYP19A1PRSS1 | |
| SCHEMBL28327575 | 0.78 | PRSS1 (0.43) | ELANEATML3MBTL1CYP19A1GAA | |
| SCHEMBL9305068 | 0.75 | ALDH1A1 (0.50) | ATML3MBTL1CYP19A1PRSS1PRSS2 | |
| SCHEMBL9305059 | 0.75 | ALDH1A1 (0.50) | ATML3MBTL1CYP19A1PRSS1PRSS2 | |
| SCHEMBL3740302 | 0.75 | ELANE (0.55) | ELANEATML3MBTL1GAALMNA | |
| SCHEMBL197674 | 0.75 | ELANE (0.55) | ELANEATML3MBTL1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992015547-A1 | ESTERS OF UNSYMMETRICALLY 2-SUBSTITUTED GLYCOLIC ACID DIMERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-09-17 | — | — | WO | disclosed |