Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302287 | 0.87 | LMNA (0.35) | LMNATDP1ATMGSTP1HCAR2 | |
| SCHEMBL9304205 | 0.87 | LMNA (0.35) | LMNATDP1ATMGSTP1HCAR2 | |
| SCHEMBL9303062 | 0.82 | TSHR (0.46) | LMNATDP1 | |
| SCHEMBL9576325 | 0.79 | ATM (0.45) | LMNATDP1ATMHCAR2CHRNB2 | |
| SCHEMBL182416 | 0.77 | TDP1 (0.51) | LMNATDP1ATMGSTP1HCAR2 | |
| SCHEMBL182415 | 0.77 | TDP1 (0.51) | LMNATDP1ATMGSTP1HCAR2 | |
| SCHEMBL573682 | 0.75 | ATM (0.41) | LMNATDP1ATMGSTP1HCAR2 | |
| SCHEMBL573681 | 0.75 | ATM (0.41) | LMNATDP1ATMGSTP1HCAR2 | |
| SCHEMBL8467471 | 0.75 | ATM (0.39) | LMNATDP1ATMHCAR2CHRNB2 | |
| SCHEMBL30181532 | 0.75 | TSHR (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11427666-B2 | Silicone-containing acrylic polymers for transdermal drug delivery compositions | NOVEN PHARMACEUTICALS, INC. (US) | 2022-08-30 | — | — | US | disclosed |
| US-20200277424-A1 | SILICONE-CONTAINING ACRYLIC POLYMERS FOR TRANSDERMAL DRUG DELIVERY COMPOSITIONS | NOVEN PHARMACEUTICALS, INC. (US) | 2020-09-03 | — | — | US | disclosed |
| EP-3179989-B1 | SILICONE-CONTAINING ACRYLIC POLYMERS FOR TRANSDERMAL DRUG DELIVERY COMPOSITIONS | NOVEN PHARMA (US) | 2019-06-12 | — | — | EP | disclosed |
| EP-3179989-A1 | SILICONE-CONTAINING ACRYLIC POLYMERS FOR TRANSDERMAL DRUG DELIVERY COMPOSITIONS | Noven Pharmaceuticals, INC. (US) | 2017-06-21 | — | — | EP | disclosed |
| US-20160030362-A1 | SILICONE-CONTAINING ACRYLIC POLYMERS FOR TRANSDERMAL DRUG DELIVERY COMPOSITIONS | NOVEN PHARMACEUTICALS, INC. (US) | 2016-02-04 | — | — | US | disclosed |
| WO-2016018858-A1 | SILICONE-CONTAINING ACRYLIC POLYMERS FOR TRANSDERMAL DRUG DELIVERY COMPOSITIONS | NOVEN PHARMACEUTICALS, INC. (US) | 2016-02-04 | — | — | WO | disclosed |
| US-5376378-A | Transdermal drug delivery | CIBA-GEIGY CORP. (US) | 1994-12-27 | — | — | US | disclosed |
| US-5288827-A | Drug selivery | CIBA-GEIGY CORPORATION (US) | 1994-02-22 | — | — | US | disclosed |