Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 6/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 6/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9576341 | 0.93 | HCAR2 (0.55) | ATMHCAR2LMNATDP1CHRNB2 | |
| SCHEMBL9576297 | 0.81 | ATM (0.42) | ATMHCAR2LMNATDP1CHRNB2 | |
| SCHEMBL9304205 | 0.79 | LMNA (0.35) | ATMHCAR2LMNATDP1CHRNB2 | |
| SCHEMBL9302287 | 0.79 | LMNA (0.35) | ATMHCAR2LMNATDP1CHRNB2 | |
| SCHEMBL9303085 | 0.79 | LMNA (0.35) | ATMHCAR2LMNATDP1CHRNB2 | |
| SCHEMBL2475190 | 0.79 | TDP1 (0.56) | ATMHCAR2LMNATDP1CHRNB2 | |
| SCHEMBL2478667 | 0.79 | TDP1 (0.56) | ATMHCAR2LMNATDP1CHRNB2 | |
| SCHEMBL2475186 | 0.79 | TDP1 (0.56) | ATMHCAR2LMNATDP1CHRNB2 | |
| SCHEMBL9576212 | 0.78 | HCAR2 (0.50) | ATMHCAR2LMNATDP1CHRNB2 | |
| SCHEMBL9576228 | 0.77 | ATM (0.47) | ATMHCAR2LMNATDP1CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0219884-B1 | HARD CONTACT LENS MATERIAL | Tomei Sangyo Kabushiki Kaisha (JP) | 1993-09-29 | — | — | EP | disclosed |
| US-5142009-A | Crosslinked blend of fumaric acid diesters | TOMEI SANGYO KABUSHIKI KAISHA (JP) | 1992-08-25 | — | — | US | disclosed |
| US-4868260-A | OXYGEN PERMEABILITY | TOMEI SANGYO KABUSHIKI KAISHA (JP) | 1989-09-19 | — | — | US | disclosed |
| EP-0219884-A2 | Hard contact lens material | Tomei Sangyo Kabushiki Kaisha (JP) | 1987-04-29 | — | — | EP | disclosed |