Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.67 |
| ▸ | COMT | P21964 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | THRB | P10828 | 2/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.54 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9304184 | 0.90 | GRIN1 (0.63) | NTRK1COMTPKMSMN1; SMN2NPC1 | |
| SCHEMBL9304180 | 0.87 | NPC1 (0.55) | NTRK1COMTPKMSMN1; SMN2NPC1 | |
| SCHEMBL9304311 | 0.85 | NTRK1 (0.65) | NTRK1COMTPKMSMN1; SMN2NPC1 | |
| SCHEMBL31134225 | 0.82 | COMT (0.81) | COMTSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL6262306 | 0.81 | PKM (0.73) | NTRK1COMTPKMSMN1; SMN2NPC1 | |
| SCHEMBL20103646 | 0.80 | NTRK1 (1.00) | NTRK1SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL6247253 | 0.80 | HPSE (0.72) | NTRK1PKMSMN1; SMN2NPC1RAB9A | |
| SCHEMBL6243599 | 0.80 | SMN1; SMN2 (0.60) | NTRK1PKMSMN1; SMN2NPC1RAB9A | |
| SCHEMBL7274899 | 0.79 | ALDH1A1 (0.68) | PKMSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL2878961 | 0.78 | HSD17B10 (0.66) | PKMSMN1; SMN2NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | claimed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | claimed |
| US-5314880-A | Platelet activating factor antagonist | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-05-24 | — | — | US | disclosed |
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | disclosed |