Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 4/20 | 0.49 |
| ▸ | CA12 | O43570 | 3/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA9 | Q16790 | 3/20 | 0.49 |
| ▸ | CA4 | P22748 | 2/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 3/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4070721 | 0.78 | LMNA (0.55) | LMNACA2CA12CA1CA9 | |
| SCHEMBL519750 | 0.75 | LMNA (0.61) | LMNACA2CA12CA1CA9 | |
| SCHEMBL9306186 | 0.73 | LMNA (0.49) | LMNACA2CA12CA1CA9 | |
| SCHEMBL20930301 | 0.72 | ALDH1A1 (0.49) | LMNACA2CA12CA1CA9 | |
| SCHEMBL2868837 | 0.72 | LMNA (0.61) | LMNACA2CA12CA1CA9 | |
| SCHEMBL30764017 | 0.72 | LMNA (0.61) | LMNACA2CA12CA1CA9 | |
| SCHEMBL29405930 | 0.71 | ALDH1A1 (0.69) | LMNACA2CA12CA1CA9 | |
| SCHEMBL2480051 | 0.71 | ALDH1A1 (0.69) | LMNACA2CA12CA1CA9 | |
| SCHEMBL10860489 | 0.71 | LMNA (0.55) | LMNACA2CA12CA1CA9 | |
| SCHEMBL8251507 | 0.70 | LMNA (0.53) | LMNACA2CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5360802-A | Antagonists of cholecystokinin and gastrin | MERCK SHARPE & DOHME LTD. | 1994-11-01 | — | — | US | disclosed |