Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | ACR | P10323 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.48 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8851291 | 0.90 | MAPT (0.52) | THRBMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9193043 | 0.90 | THRB (0.60) | THRBMAPTSMN1; SMN2NPC1PRSS1 | |
| SCHEMBL8026374 | 0.87 | NPC1 (0.52) | MAPTSMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL7619158 | 0.87 | NPC1 (0.52) | MAPTSMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL8913388 | 0.86 | THRB (0.61) | THRBMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL8913348 | 0.86 | THRB (0.61) | THRBMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL8850790 | 0.86 | LMNA (0.53) | THRBMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL8962712 | 0.86 | LMNA (0.60) | MAPTSMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL30354554 | 0.85 | THRB (0.62) | THRBMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL10633416 | 0.85 | THRB (0.62) | THRBMAPTSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5304667-A | Cyclosiloxanes containing mesogenic side groups | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1994-04-19 | — | — | US | disclosed |
| US-5221759-A | CYCLOSILOXANES CONTAINING MESOGENIC SIDE GROUPS | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1993-06-22 | — | — | US | disclosed |