Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 7/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7941063 | 0.86 | TDP1 (0.45) | KDM4EMEN1RECQLKMT2ATDP1 | |
| SCHEMBL27676784 | 0.86 | TDP1 (0.45) | KDM4EMEN1RECQLKMT2ATDP1 | |
| SCHEMBL9674085 | 0.82 | GPR84 (0.49) | TDP1CNR2FAAHALDH1A1ZDHHC2 | |
| SCHEMBL27710414 | 0.81 | GPR84 (0.51) | CNR2FAAHALDH1A1ZDHHC2PRSS1 | |
| SCHEMBL28400543 | 0.81 | GPR84 (0.51) | CNR2FAAHALDH1A1ZDHHC2PRSS1 | |
| SCHEMBL28512575 | 0.81 | GPR84 (0.51) | CNR2FAAHALDH1A1ZDHHC2PRSS1 | |
| SCHEMBL7108920 | 0.81 | GPR84 (0.51) | CNR2FAAHALDH1A1ZDHHC2PRSS1 | |
| SCHEMBL7112547 | 0.81 | GPR84 (0.51) | CNR2FAAHALDH1A1ZDHHC2PRSS1 | |
| SCHEMBL11977567 | 0.79 | ALOX5 (0.41) | KDM4EMEN1RECQLKMT2ATDP1 | |
| SCHEMBL9303074 | 0.79 | ELANE (0.46) | KDM4EMEN1KMT2AELANEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5326887-A | Reacting ester of alpha hydroxy acid oligomer over fixed bed catalyst | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-07-05 | — | — | US | disclosed |
| WO-1992015572-A1 | PROCESS FOR THE PREPARATION OF 1,4-DIOXANE-2,5-DIONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-09-17 | — | — | WO | disclosed |